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<gallery caption="Lyme genomics" widths=200px perrow=4>
<gallery caption="Lyme genomics" widths=200px perrow=4>
File: Spectrum.01743-22-f003.gif | Li, Li; Di, Lia; Zeglis, Brian M.; Qiu, Weigang. 2022. “Evolution of the ''vls'' antigenic variability locus of the Lyme Disease pathogen and development of recombinant monoclonal antibodies targeting conserved VlsE epitopes”. '''''Microbial Spectrum''''' 10 (5):1-15. DOI: https://doi.org/10.1128/spectrum.01743-22
File: Spectrum.01743-22-f003.gif | Li, Li; Di, Lia; Zeglis, Brian M.; Qiu, Weigang. 2022. “Evolution of the ''vls'' antigenic variability locus of the Lyme Disease pathogen and development of recombinant monoclonal antibodies targeting conserved VlsE epitopes”. '''''Microbial Spectrum''''' 10 (5):1-15. DOI: https://doi.org/10.1128/spectrum.01743-22
File: Spectrum.01743-22-f003.gif |Di, Lia; Akther, Saymon; Bezrucenkovas, Edgaras; Ivanova, Larisa; Sulkow, Brian; Wu, Bing; Mneimneh, Saad; Gomes-Solecki, Maria; Qiu, Wei-Gang. 2021. "Maximum antigen diversification in a lyme bacterial population and evolutionary strategies to overcome pathogen diversity". '''''The ISME Journal'''''. 16, 447-464. [[https://pubmed.ncbi.nlm.nih.gov/34413477/ PMID 34413477]]
File: Fig7-small.png |Di, Lia; Akther, Saymon; Bezrucenkovas, Edgaras; Ivanova, Larisa; Sulkow, Brian; Wu, Bing; Mneimneh, Saad; Gomes-Solecki, Maria; Qiu, Wei-Gang. 2021. "Maximum antigen diversification in a lyme bacterial population and evolutionary strategies to overcome pathogen diversity". '''''The ISME Journal'''''. 16, 447-464. [[https://pubmed.ncbi.nlm.nih.gov/34413477/ PMID 34413477]]
File: Ira-fig2.png | Schwartz, Ira; Margos, Gabriele; Casjens, Sherwood R.; Qiu, Wei-Gang; Eggers, Christian H. 2020. "Multipartite Genome of Lyme Disease ''Borrelia'': Structure, Variation and Prophages". '''''Current Issues in Molecular Biology'''''. 42:409-454.  DOI: https://doi.org/10.21775/9781913652616  
File: Ira-fig2.png | Schwartz, Ira; Margos, Gabriele; Casjens, Sherwood R.; Qiu, Wei-Gang; Eggers, Christian H. 2020. "Multipartite Genome of Lyme Disease ''Borrelia'': Structure, Variation and Prophages". '''''Current Issues in Molecular Biology'''''. 42:409-454.  DOI: https://doi.org/10.21775/9781913652616  
File:Fig6-1-Barbour.png | Barbour, A. G. and Qiu, W. (2019). ''Borreliella''. In '''''Bergey's Manual of Systematics of Archaea and Bacteria''''' (eds W. B. Whitman, F. Rainey, P. Kämpfer, M. Trujillo, J. Chun, P. DeVos, B. Hedlund and S. Dedysh). John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: https://doi.org/10.1002/9781118960608.gbm01525
File:Fig6-1-Barbour.png | Barbour, A. G. and Qiu, W. (2019). ''Borreliella''. In '''''Bergey's Manual of Systematics of Archaea and Bacteria''''' (eds W. B. Whitman, F. Rainey, P. Kämpfer, M. Trujillo, J. Chun, P. DeVos, B. Hedlund and S. Dedysh). John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: https://doi.org/10.1002/9781118960608.gbm01525

Revision as of 19:27, 21 March 2023

Welcome to Dr Weigang Qiu's Lab Wiki: Directions by Google Map

Weigang Qiu, Ph.D., Professor
Department of Biological Sciences
Hunter College of City University of New York
Belfer Research Building, Room 402
413 East  69th Street, New York, NY 10021
Office: 1-212-896-0445; Email: wqiu-at-(hunter.cuny.edu)

Lab Resources

Lab publications (last update: March 20, 2023)

  • Lyme genomics
  • Li, Li; Di, Lia; Zeglis, Brian M.; Qiu, Weigang. 2022. “Evolution of the vls antigenic variability locus of the Lyme Disease pathogen and development of recombinant monoclonal antibodies targeting conserved VlsE epitopes”. Microbial Spectrum 10 (5):1-15. DOI: https://doi.org/10.1128/spectrum.01743-22

    Li, Li; Di, Lia; Zeglis, Brian M.; Qiu, Weigang. 2022. “Evolution of the vls antigenic variability locus of the Lyme Disease pathogen and development of recombinant monoclonal antibodies targeting conserved VlsE epitopes”. Microbial Spectrum 10 (5):1-15. DOI: https://doi.org/10.1128/spectrum.01743-22

  • Di, Lia; Akther, Saymon; Bezrucenkovas, Edgaras; Ivanova, Larisa; Sulkow, Brian; Wu, Bing; Mneimneh, Saad; Gomes-Solecki, Maria; Qiu, Wei-Gang. 2021. "Maximum antigen diversification in a lyme bacterial population and evolutionary strategies to overcome pathogen diversity". The ISME Journal. 16, 447-464. [PMID 34413477]

    Di, Lia; Akther, Saymon; Bezrucenkovas, Edgaras; Ivanova, Larisa; Sulkow, Brian; Wu, Bing; Mneimneh, Saad; Gomes-Solecki, Maria; Qiu, Wei-Gang. 2021. "Maximum antigen diversification in a lyme bacterial population and evolutionary strategies to overcome pathogen diversity". The ISME Journal. 16, 447-464. [PMID 34413477]

  • Schwartz, Ira; Margos, Gabriele; Casjens, Sherwood R.; Qiu, Wei-Gang; Eggers, Christian H. 2020. "Multipartite Genome of Lyme Disease Borrelia: Structure, Variation and Prophages". Current Issues in Molecular Biology. 42:409-454. DOI: https://doi.org/10.21775/9781913652616

    Schwartz, Ira; Margos, Gabriele; Casjens, Sherwood R.; Qiu, Wei-Gang; Eggers, Christian H. 2020. "Multipartite Genome of Lyme Disease Borrelia: Structure, Variation and Prophages". Current Issues in Molecular Biology. 42:409-454. DOI: https://doi.org/10.21775/9781913652616

  • Barbour, A. G. and Qiu, W. (2019). Borreliella. In Bergey's Manual of Systematics of Archaea and Bacteria (eds W. B. Whitman, F. Rainey, P. Kämpfer, M. Trujillo, J. Chun, P. DeVos, B. Hedlund and S. Dedysh). John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: https://doi.org/10.1002/9781118960608.gbm01525

    Barbour, A. G. and Qiu, W. (2019). Borreliella. In Bergey's Manual of Systematics of Archaea and Bacteria (eds W. B. Whitman, F. Rainey, P. Kämpfer, M. Trujillo, J. Chun, P. DeVos, B. Hedlund and S. Dedysh). John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: https://doi.org/10.1002/9781118960608.gbm01525

  • Evolution as learning algorithms
    • Ely, B.; Koh, W.; Ho, E.; Hassan, T.M.; Pham, A.V.; Qiu, W. (2023). Novelty Search Promotes Antigenic Diversity in Microbial Pathogens. Pathogens 12:388. DOI: https://doi.org/10.3390/pathogens12030388
    • Attie O, Sulkow B, Di C, Qiu W (2019). Genetic codes optimized as a traveling salesman problem. PLoS ONE 14(10): e0224552. DOI: https://doi.org/10.1371/journal.pone.0224552
    • Jinyuan Yan, Maxime Deforet, Kerry E. Boyle, Rayees Rahman, Raymond Liang, Chinweike Okegbe, Lars E. P. Dietrich, Weigang Qiu, Joao B. Xavier. 2017. Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network. PLoS Comput Biol 13(8): e1005677. DOI: https://doi.org/10.1371/journal.pcbi.1005677
  • Informatics tool development
    • Hernandez Y, Bernstein R, Pagan P, Vargas, L, McCaig W, Ramrattan G, Akther S, Larracuente A, Di L, Vieira FG, Qiu WG*. 2018. BbWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines. BMC Bioinformatics 19(1):76. [PMID 29499649]
    • Lia Di, Pedro E Pagan, Daniel Packer, Che L Martin, Saymon Akther, Girish Ramrattan, Emmanuel F Mongodin, Claire M Fraser, Steven E Schutzer, Benjamin J Luft, Sherwood R Casjens and Wei-Gang Qiu*. 2014. BorreliaBase: a phylogeny-centered browser of Borrelia genomes. BMC Bioinformatics 15:233. [PMID 24994456]
  • Full publication lists

Getting started

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