Year 2019

TD Project

• Credit: Christopher Panlasigui
• Brief computational/statistical steps:

1. Quantile normalization between all replicates (with log2 transformatuon)
2. Linear model among the 3 groups
3. Select top significant genes
4. Map gene names
5. Cluster and show by interactive heatmaps in R

• Results

1. Heatmap 1. Scaled by gene
2. heatmap of top differentiately expressed genes (p<0.001, 1e-5). Values are Fold Change over mean Wild Type