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| [[Portrait-2022-blur.jpg|150px|thumb]]  
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| <center> <strong>Welcome to Qiu Lab Wiki @ Hunter</strong><br>Weigang Qiu, Ph.D., Professor<br> [http://biology.hunter.cuny.edu Department of Biological Sciences]<br>
| <center> <strong>Welcome to Qiu Lab Wiki @ Hunter</strong><br>Weigang Qiu, Ph.D., Professor<br> [http://biology.hunter.cuny.edu Department of Biological Sciences]<br>
[https://hunter.cuny.edu Hunter College] of<br> [https://www.cuny.edu City University of New York]<br> Belfer Research Building, Room 402<br>413 East  69th Street, New York, NY 10021<br>Office: 1-212-896-0445<br>Email: wqiu-at-(hunter.cuny.edu)<br>[https://goo.gl/maps/xv1KmaW3XEnxaY1V7 Directions by Google Map] </center>
[https://hunter.cuny.edu Hunter College] of<br> [https://www.cuny.edu City University of New York]<br> Belfer Research Building, Room 402<br>413 East  69th Street, New York, NY 10021<br>Office: 1-212-896-0445<br>Email: wqiu-at-(hunter.cuny.edu)<br> </center>
| [[File:Belfer_building.jpg]]  
| [[File:Belfer_building.jpg | x300px | thumb | [https://goo.gl/maps/xv1KmaW3XEnxaY1V7 Directions by Google Map]]]  
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===Lyme Genomics===
===Lyme Genomics===
<gallery mode="packed" heights="200px" perrow="4" style="text-align:left">
<gallery mode="packed" heights="200px" perrow="4" style="text-align:left">
File:Spectrum.01743-22-f003.gif |Li, Di, Zeglis, Qiu (2022). “Evolution of the ''vls'' antigenic variability locus of the Lyme Disease pathogen and development of recombinant monoclonal antibodies targeting conserved VlsE epitopes”. '''''Microbial Spectrum''''' 10 (5):1-15. DOI: https://doi.org/10.1128/spectrum.01743-22
File:Spectrum.01743-22-f003.gif | link=https://doi.org/10.1128/spectrum.01743-22  | Li, Di, Zeglis, Qiu (2022). “Evolution of the ''vls'' antigenic variability locus of the Lyme Disease pathogen and development of recombinant monoclonal antibodies targeting conserved VlsE epitopes”. '''''Microbial Spectrum''''' 10 (5):1-15.  
File:Fig7-small.png|Di*, Akther*, Bezrucenkovas, Ivanova, Sulkow, Wu, Mneimneh, Gomes-Solecki, Qiu (2021). "Maximum antigen diversification in a lyme bacterial population and evolutionary strategies to overcome pathogen diversity". '''''The ISME Journal'''''. 16, 447-464. [[https://pubmed.ncbi.nlm.nih.gov/34413477/ PMID 34413477]] (*co-first authors)
File:Fig7-small.png | link= https://pubmed.ncbi.nlm.nih.gov/34413477 | Di*, Akther*, Bezrucenkovas, Ivanova, Sulkow, Wu, Mneimneh, Gomes-Solecki, Qiu (2021). "Maximum antigen diversification in a lyme bacterial population and evolutionary strategies to overcome pathogen diversity". '''''The ISME Journal'''''. 16, 447-464. (*co-first authors)
File:Ira-fig2.png|Schwartz, Margos, Casjens, Qiu, Eggers (2020). "Multipartite Genome of Lyme Disease ''Borrelia'': Structure, Variation and Prophages". '''''Current Issues in Molecular Biology'''''. 42:409-454. DOI: https://doi.org/10.21775/9781913652616
File:Ira-fig2.png | link=https://doi.org/10.21775/9781913652616 | Schwartz, Margos, Casjens, Qiu, Eggers (2020). "Multipartite Genome of Lyme Disease ''Borrelia'': Structure, Variation and Prophages". '''''Current Issues in Molecular Biology'''''. 42:409-454.  
File:Fig6-1-Barbour.png|Barbour & Qiu (2019). ''Borreliella''. In '''''Bergey's Manual of Systematics of Archaea and Bacteria''''' (eds W. B. Whitman, F. Rainey, P. Kämpfer, M. Trujillo, J. Chun, P. DeVos, B. Hedlund and S. Dedysh). John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: https://doi.org/10.1002/9781118960608.gbm01525
File:Fig6-1-Barbour.png | link=https://doi.org/10.1002/9781118960608.gbm01525 | Barbour & Qiu (2019). ''Borreliella''. In '''''Bergey's Manual of Systematics of Archaea and Bacteria'''''. John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI:  
</gallery>
</gallery>


===Evolution & Learning Algorithms===
===Evolution & Learning Algorithms===
<gallery mode="packed" heights="200px" perrow="3" style="text-align:left">
<gallery mode="packed" heights="200px" perrow="3" style="text-align:left">
File:Pathogens-12-00388-g003.png|Ely, Koh, Ho, Hassan, Pham, Qiu (2023). Novelty Search Promotes Antigenic Diversity in Microbial Pathogens. '''''Pathogens''''' 12:388. DOI: https://doi.org/10.3390/pathogens12030388
File:Pathogens-12-00388-g003.png | link=https://doi.org/10.3390/pathogens12030388 | Ely, Koh, Ho, Hassan, Pham, Qiu (2023). Novelty Search Promotes Antigenic Diversity in Microbial Pathogens. '''''Pathogens''''' 12:388.
File:Pone.0224552.g005.png|Attie, Sulkow, Di, Qiu (2019). Genetic codes optimized as a traveling salesman problem. '''''PLoS ONE''''' 14(10): e0224552. DOI: https://doi.org/10.1371/journal.pone.0224552
File:Pone.0224552.g005.png | link=https://doi.org/10.1371/journal.pone.0224552 | Attie, Sulkow, Di, Qiu (2019). Genetic codes optimized as a traveling salesman problem. '''''PLoS ONE''''' 14(10): e0224552.
File:Pcbi.1005677.g001.png|Yan, Deforet, Boyle, Rahman, Liang, Okegbe, Dietrich, Qiu, Xavier (2017). Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network. '''''PLoS Comput Biol''''' 13(8): e1005677. DOI: https://doi.org/10.1371/journal.pcbi.1005677
File:Pcbi.1005677.g001.png | link=https://doi.org/10.1371/journal.pcbi.1005677 | Yan, Deforet, Boyle, Rahman, Liang, Okegbe, Dietrich, Qiu, Xavier (2017). Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network. '''''PLoS Comput Biol''''' 13(8): e1005677.  
</gallery>
</gallery>


===Informatics Tool Development===
===Informatics Tool Development===
<gallery mode="packed" heights="200px" style="text-align:left">
<gallery mode="packed" heights="200px" style="text-align:left">
File: 12859 2018 2074 Fig1 HTML.png | Hernandez, Bernstein, Pagan, Vargas, McCaig, Ramrattan, Akther, Larracuente, Di, Vieira, Qiu. (2018). BbWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines. '''''BMC Bioinformatics''''' 19(1):76. [[https://pubmed.ncbi.nlm.nih.gov/29499649/ PMID 29499649]]
File: 12859 2018 2074 Fig1 HTML.png | link=https://pubmed.ncbi.nlm.nih.gov/29499649 | Hernandez, Bernstein, Pagan, Vargas, McCaig, Ramrattan, Akther, Larracuente, Di, Vieira, Qiu. (2018). BbWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines. '''''BMC Bioinformatics''''' 19(1):76.
File: 12859 2014 Article 6488 Fig3 HTML.png | Di, Pagan, Packer, Martin, Akther, Ramrattan, Mongodin, Fraser, Schutzer, Luft, Casjens and Qiu. (2014). BorreliaBase: a phylogeny-centered browser of ''Borrelia'' genomes. '''''BMC Bioinformatics''''' 15:233. [[https://pubmed.ncbi.nlm.nih.gov/24994456/ PMID 24994456]]
File: 12859 2014 Article 6488 Fig3 HTML.png | link=https://pubmed.ncbi.nlm.nih.gov/24994456 | Di, Pagan, Packer, Martin, Akther, Ramrattan, Mongodin, Fraser, Schutzer, Luft, Casjens and Qiu. (2014). BorreliaBase: a phylogeny-centered browser of ''Borrelia'' genomes. '''''BMC Bioinformatics''''' 15:233.
</gallery>
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* Dr James Haven (2011): CUNY Grad Center, Biology/MCD
* Dr James Haven (2011): CUNY Grad Center, Biology/MCD
* Dr Tika Sukarna (2009): CUNY Grad Center, Biology/MCD
* Dr Tika Sukarna (2009): CUNY Grad Center, Biology/MCD
* Dr Juan Coronado (2008): CUNY Grad Center, Biology/MCD (with Dr Peter Lipke)
* Dr Juan Coronado (2008): CUNY Grad Center, Biology/MCD (Dr Peter Lipke)
* Dr William McCaig: CUNY BA, Ph.D. from Stony Brook University
* Dr William McCaig: CUNY BA, Ph.D. from Stony Brook University
* Dr Vincent Xue: CUNY CS/Bioinformatics, Ph.D. from MIT  
* Dr Vincent Xue: CUNY CS/Bioinformatics, Ph.D. from MIT  
* Dr Fubin Li: CUNY Grad Center, Biology/MCD
* Dr Fubin Li: CUNY Grad Center, Biology/MCD (Dr Laurel Eckhardt)
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(published coauthors)<br>
(published coauthors)<br>
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==Web Apps==
==Web Apps==
===Collaborative works===
===Apps with Collaborators===
<gallery mode="packed" heights="200px" perrow="4" style="text-align:left">
<gallery mode="packed" heights="200px" perrow="4" style="text-align:left">
File:Screenshot_2023-03-24_122016.png| link=http://borreliabase.org/~wgqiu/clickme-khalikuz/temp-Points.html | Phosphoproteome MDM2KD data set (with Bargonetti Lab @Hunter)
File: Silac.png | link=http://borreliabase.org/~wgqiu/Polotskaia_etal_2014/supp-fig-s1/ | Data & [http://borreliabase.org/~wgqiu/Polotskaia_etal_2014/supp-table-s1/ GSEA] associated with Polotskaia_etal_2014 (with Bargonetti Lab @Hunter)
File:Screenshot_2023-03-24_122312.png| link=http://borreliabase.org/~wgqiu/mpai-v3/ | Genes & Pathways Associated with mTP53 (with Bargonetti Lab @Hunter)
File:Screenshot_2023-03-24_122016.png | link=http://borreliabase.org/~wgqiu/clickme-khalikuz/temp-Points.html | Phosphoproteome MDM2KD data set (with Bargonetti Lab @Hunter)
File:Screenshot_2023-03-24_122312.png | link=http://borreliabase.org/~wgqiu/mpai-v3/ | Genes & Pathways Associated with mTP53 (with Bargonetti Lab @Hunter)
File:Spombe.png | link=Spombe | S. pombe transcriptomes (with Zhong Lab @Hunter)
File:Screenshot 2023-03-24 122223.png | link=http://borreliabase.org/~wgqiu/gbs-browser-v3/ | Group B Streptococcus (GBS) genome browser (with Wu Lab @Shenzhen)
File:Screenshot 2023-03-24 122223.png | link=http://borreliabase.org/~wgqiu/gbs-browser-v3/ | Group B Streptococcus (GBS) genome browser (with Wu Lab @Shenzhen)
File:Screenshot 2023-03-24 122245.png | link=http://borreliabase.org/~wgqiu/oneKGenome/ | 1K genome (with Ogunwobi Lab @Hunter)
File:Screenshot 2023-03-24 122245.png | link=http://borreliabase.org/~wgqiu/oneKGenome/ | 1K genome (with Ogunwobi Lab @Hunter)
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==SARS-CoV-2 genome evolution==
==SARS-CoV-2 genome evolution==
<gallery mode="packed" heights="200px" perrow="3" style="text-align:left">
<gallery mode="packed" heights="200px" perrow="3" style="text-align:left">
File:Cov-fig1.jpg|Akther, Bezrucenkovas, Sulkow, Panlasigui, Qiu, Di (April, 2020). "CoV Genome Tracker: tracing genomic footprints of Covid-19 pandemic". '''''[https://www.biorxiv.org/content/biorxiv/early/2020/04/14/2020.04.10.036343.full.pdf BioRxiv]'''''; Web app: SARS-CoV-2 Genome Tracker; Github: https://github.com/weigangq/cov-browser
File:Cov-fig1.jpg | Akther, Bezrucenkovas, Sulkow, Panlasigui, Qiu, Di (April, 2020). "CoV Genome Tracker: tracing genomic footprints of Covid-19 pandemic". '''''[https://www.biorxiv.org/content/biorxiv/early/2020/04/14/2020.04.10.036343.full.pdf BioRxiv]'''''; Web app: SARS-CoV-2 Genome Tracker; Github: https://github.com/weigangq/cov-browser
File:Rec-fig2.png|Akther, Li, Martin, Di, Sulkow, Pante, Bezrucenlovas, Luft, Qiu (May, 2020). "Origin, recombination, and missed opprotunities:  a genomic perspective of the first 100 days of COVID-19 pandemic". (Unpublished).
File:Rec-fig2.png | Akther, Li, Martin, Di, Sulkow, Pante, Bezrucenlovas, Luft, Qiu (May, 2020). "Origin, recombination, and missed opprotunities:  a genomic perspective of the first 100 days of COVID-19 pandemic". (Unpublished).
File:Cov-fig3-trace.png|Akther, Bezrucenlovas, Li, Sulkow, Di, Pante, Martin, Luft, Qiu (Sep, 2021). "Following the Trail of One Million Genomes: Footprints of SARS-CoV-2 Adaptation to Humans". '''''[https://www.biorxiv.org/content/biorxiv/early/2021/05/10/2021.05.07.443114.full.pdf BioRxiv link]''''': . Github:  https://github.com/weigangq/cov-db
File:Cov-fig3-trace.png | Akther, Bezrucenlovas, Li, Sulkow, Di, Pante, Martin, Luft, Qiu (Sep, 2021). "Following the Trail of One Million Genomes: Footprints of SARS-CoV-2 Adaptation to Humans". '''''[https://www.biorxiv.org/content/biorxiv/early/2021/05/10/2021.05.07.443114.full.pdf BioRxiv link]''''': . Github:  https://github.com/weigangq/cov-db
</gallery>
</gallery>



Revision as of 21:05, 27 March 2023

Portrait-2022-blur.jpg
Welcome to Qiu Lab Wiki @ Hunter
Weigang Qiu, Ph.D., Professor
Department of Biological Sciences
Hunter College of
City University of New York
Belfer Research Building, Room 402
413 East  69th Street, New York, NY 10021
Office: 1-212-896-0445
Email: wqiu-at-(hunter.cuny.edu)

Lab publications

Lyme Genomics

Evolution & Learning Algorithms

Informatics Tool Development

last update: March 20, 2023

Lab members and trainees

Year/Period Doctoral members & trainees Other members & trainees
Current Academic Year

(Fall 2022, Spring 2023 & Summer 2023)

  • Li Li (Lily): CUNY Grad Center, Biology/EEB doctoral program
  • Brandon Ely: CUNY Grad Center, Biology/MCD doctoral program
  • Dr Yozen Hernandez: System administrator (part-time), Ph.D. from Boston University
  • Dr Oliver Attie: Research associate (volunteer), Ph.D. from NYU
  • Tasmina Hassan: Hunter Bio/CS
  • Mathew DiCicco: Hunter Math/CS
  • Tara Doma Lama: Hunter Bio/Bioinformatics
  • Hagar Abuzaid: Hunter Bio
Alumni (Since Fall 2002)
  • Dr Lia Di: Ph.D. from Nanjing Agricultural University & Wisconsin Blood Institute
  • Dr Saymon Akther (2022): CUNY Grad Center, Biology/EEB
  • Dr Rayees Rahman: Hunter Bio/Bioinformatics, Ph.D. from Mt Sinai Medical School
  • Dr Che Martin (2013): CUNY Grad Center, Biology/MCD
  • Dr James Haven (2011): CUNY Grad Center, Biology/MCD
  • Dr Tika Sukarna (2009): CUNY Grad Center, Biology/MCD
  • Dr Juan Coronado (2008): CUNY Grad Center, Biology/MCD (Dr Peter Lipke)
  • Dr William McCaig: CUNY BA, Ph.D. from Stony Brook University
  • Dr Vincent Xue: CUNY CS/Bioinformatics, Ph.D. from MIT
  • Dr Fubin Li: CUNY Grad Center, Biology/MCD (Dr Laurel Eckhardt)

(published coauthors)

  • Brian Sulkow: CUNY Grad Center, Mathematics
  • Winston Koh: Hunter Bio/CS
  • Eamen Ho: Hunter Bio/Bioinformatics
  • Ahn Pham: Hunter Bio/Bioinformatics
  • Chris Panlasigui: Hunter Bio/Bioinformatics
  • Amanda Amanda Larracuente: CUNY Grad Center, Biology/MCD
  • Pedro Pagan: Hunter Bio/Bioinformatics
  • Edgaras Bezrucenkovas: Hunter Chem/Bioinformatics
  • Girish Ramrattan: Hunter Bio/Bioinformatics
  • Levy Vargas: Hunter Bio/Bioinformatics
  • Chong Di: Hunter Geography
  • Roy Nunez: Hunter Bio
  • Mei Wu: CUNY City Tech
  • Desiree Pante: Hunter Bio
  • Saimtun Shipa: Hunter Stat (MA)
  • Bing Wu: Hunter Bio/Biotechnology
  • Svidatoslav Kendall (Slav): Hunter Biology
  • Philip Romov: Hunter CS

Web Apps

Apps with Collaborators

Qiu Lab Apps

Teaching & Curricular Development

SARS-CoV-2 genome evolution

Lab Resources & Protocols

Wiki Help