Main Page

Welcome to the Wiki for Dr. Qiu's Evolutionary Bioinformatics Lab at Hunter College!

• Site under construction
• Current official website: http://qiu.bioweb.hunter.cuny.edu.

Lab Gallery

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  A female adult Lyme tick (Ixodes scapularis) waiting for passing hosts

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  The same tick moving

Research Interests

• Evolution, microbial diversity, and pathogen genomics. I am interested in the population genomics of microbial species. The main focus of my lab is the comparative analysis of multiple genomes of the Lyme disease pathogen. The goals of my research include reconstructing the history of worldwide diversification of the Lyme disease bacteria, an understanding of the mechanisms of their genome evolution (e.g., the roles of recombination and natural selection), and inference of gene and genome functions.

• Bioinformatics & fieldwork. I use computational and statistical approaches to test evolutionary and functional hypotheses. Students learn and use modern computational tools such as relational database/SQL, Perl/BioPerl, and statistical computing with R.

Teaching & Courses

• BIOL 425/790.49 Computational Molecular Biology (Spring 2011 Syllabus)
• BIOL 375/790.64 Molecular Evolution [1]
• The QuBi Curricular Improvement Project in Quantitative Biology [2]

Software Development

• Borrelia Ortholog Retriever Obtain ortholog alignments from 23 Borrelia spp genomes. Search by gene names and IDs.[3]
• SimBac A package for simulating bacterial genome evolution [4]
• DNATweezer: A Perl wrapper of some BioPerl modules [5]