Year 2019

TD Project

• Credit: Christopher Panlasigui
• Main computational steps:

1. Quantile normalization between all replicates (with log2 transformatuon)
2. Linear model among the 3 groups
3. Select top significant genes
4. Map gene names
5. Cluster and show by interactive heatmaps in R
   1. Heatmap 1. Scaled perl row
   2. heatmap of top differentiately expressed genes (p<0.001, 1e-3). Values are Fold Change over mean Wild Tyoe