Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_S_PHASE |
| Enrichment Score (ES) | 0.457789 |
| Normalized Enrichment Score (NES) | 1.772511 |
| Nominal p-value | 0.0016025641 |
| FDR q-value | 0.024796331 |
| FWER p-Value | 0.266 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 36 | 2.572 | 0.0468 | Yes |
| 2 | MCM2 | MCM2 Entrez, Source | MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) | 59 | 2.326 | 0.0923 | Yes |
| 3 | MCM3 | MCM3 Entrez, Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 70 | 2.223 | 0.1391 | Yes |
| 4 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 79 | 2.170 | 0.1853 | Yes |
| 5 | ORC1 | 94 | 2.080 | 0.2277 | Yes | ||
| 6 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 105 | 2.044 | 0.2704 | Yes |
| 7 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 137 | 1.781 | 0.3010 | Yes |
| 8 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 169 | 1.622 | 0.3281 | Yes |
| 9 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 234 | 1.421 | 0.3407 | Yes |
| 10 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 238 | 1.412 | 0.3714 | Yes |
| 11 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 247 | 1.393 | 0.4002 | Yes |
| 12 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 274 | 1.344 | 0.4225 | Yes |
| 13 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 340 | 1.183 | 0.4295 | Yes |
| 14 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 447 | 1.003 | 0.4202 | Yes |
| 15 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 474 | 0.974 | 0.4342 | Yes |
| 16 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 511 | 0.930 | 0.4443 | Yes |
| 17 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 594 | 0.851 | 0.4387 | Yes |
| 18 | PSME4 | PSME4 Entrez, Source | proteasome (prosome, macropain) activator subunit 4 | 595 | 0.851 | 0.4578 | Yes |
| 19 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 680 | 0.759 | 0.4496 | No |
| 20 | RFC5 | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 764 | 0.685 | 0.4400 | No |
| 21 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 780 | 0.674 | 0.4506 | No |
| 22 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 879 | 0.597 | 0.4346 | No |
| 23 | SKP1 | 897 | 0.583 | 0.4426 | No | ||
| 24 | ORC5 | 958 | 0.546 | 0.4368 | No | ||
| 25 | ORC3 | 971 | 0.538 | 0.4453 | No | ||
| 26 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 1014 | 0.515 | 0.4442 | No |
| 27 | MAX | MAX Entrez, Source | MYC associated factor X | 1059 | 0.490 | 0.4420 | No |
| 28 | PSMB6 | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 1117 | 0.450 | 0.4350 | No |
| 29 | PSMA5 | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 1120 | 0.447 | 0.4444 | No |
| 30 | PSMB2 | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 1243 | 0.379 | 0.4163 | No |
| 31 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 1280 | 0.355 | 0.4134 | No |
| 32 | ORC2 | 1298 | 0.346 | 0.4161 | No | ||
| 33 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 1398 | 0.283 | 0.3927 | No |
| 34 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 1435 | 0.261 | 0.3878 | No |
| 35 | PSMA3 | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 1487 | 0.225 | 0.3775 | No |
| 36 | PSMA4 | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 1518 | 0.200 | 0.3730 | No |
| 37 | CCNH | CCNH Entrez, Source | cyclin H | 1539 | 0.187 | 0.3712 | No |
| 38 | PSMB1 | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 1571 | 0.168 | 0.3657 | No |
| 39 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 1592 | 0.158 | 0.3632 | No |
| 40 | CUL1 | CUL1 Entrez, Source | cullin 1 | 1701 | 0.091 | 0.3329 | No |
| 41 | PSMB3 | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 1731 | 0.073 | 0.3258 | No |
| 42 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 1739 | 0.066 | 0.3252 | No |
| 43 | PSMC6 | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 1759 | 0.054 | 0.3207 | No |
| 44 | PSMC5 | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 1784 | 0.038 | 0.3143 | No |
| 45 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 1811 | 0.028 | 0.3072 | No |
| 46 | PSMD14 | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 1832 | 0.013 | 0.3015 | No |
| 47 | PSMA2 | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 1911 | -0.047 | 0.2791 | No |
| 48 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 1974 | -0.087 | 0.2625 | No |
| 49 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 2015 | -0.115 | 0.2531 | No |
| 50 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 2028 | -0.127 | 0.2523 | No |
| 51 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 2033 | -0.133 | 0.2541 | No |
| 52 | PSMD11 | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 2082 | -0.168 | 0.2435 | No |
| 53 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 2091 | -0.175 | 0.2450 | No |
| 54 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 2141 | -0.209 | 0.2350 | No |
| 55 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 2163 | -0.220 | 0.2336 | No |
| 56 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 2167 | -0.223 | 0.2377 | No |
| 57 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 2182 | -0.233 | 0.2387 | No |
| 58 | PSMD3 | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 2216 | -0.256 | 0.2346 | No |
| 59 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 2232 | -0.268 | 0.2361 | No |
| 60 | PSMD13 | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 2239 | -0.272 | 0.2404 | No |
| 61 | PSMD7 | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 2311 | -0.312 | 0.2260 | No |
| 62 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 2356 | -0.336 | 0.2204 | No |
| 63 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 2368 | -0.349 | 0.2249 | No |
| 64 | PSMD4 | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 2456 | -0.426 | 0.2083 | No |
| 65 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 2509 | -0.467 | 0.2032 | No |
| 66 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 2639 | -0.577 | 0.1774 | No |
| 67 | PSMD10 | PSMD10 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 3006 | -0.992 | 0.0899 | No |
| 68 | PSMD5 | PSMD5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 3166 | -1.275 | 0.0708 | No |
